The Registry Department, which was eatablished in 1977 as the administrative organ of the University, is currently headed by Dr. Haruna Aliyu. It is the central nerve organ of the University that serves as the Secretariate of all the statutory organs namely: Council, Congregation, Convocation and the Senate. The Registry is represented in almost all the committees of the University where its staff serve as the Secretaries or members/secretaries.

The Registry Department is the central organ of any University. It is very strategic to the day-to-day administration of the institution. In Bayero University, The Registry is one of the organs that were established concurrently with the University when Abdullahi Bayero College, an affiliate of Ahmadu Bello University, ABC/ABU was elected to the status of a full-fledged university by the Federal Government in 1997.

The Registry operates the Directorate System of administration, it has the Registrar's Office at the top and four other Directorates as follows: